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Kritzer, Joshua A.

Comprehensive Analysis of Loops at Protein-Protein Interfaces for Macrocycle Design

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Creator:

Gavenonis, Jason, Sheneman, Bradley A., Kritzer, Joshua A., Eshelman, Matthew R, and Siegert, Timothy R

Description:

https://www.nature.com/articles/nchembio.1580, Published as: Gavenonis, Jason, Bradley A Sheneman, Timothy R Siegert, Matthew R. Eshelman, and Joshua A. Kritzer. "Comprehensive Analysis of Loops at Protein-Protein Interfaces...

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Article
Getting in Shape: Controlling Peptide Bioactivity and Bioavailability Using Conformational Constraints

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Creator:

Bock, Jonathan E., Kritzer, Joshua A., and Gavenonis, Jason

Description:

Chemical biologists commonly seek out correlations between the physicochemical properties of molecules and their behavior in biological systems. However, a new paradigm is emerging for peptides in which conformation is...

Type:

Article
Potential C-terminal-domain Inhibitors of Heat Shock Protein 90 Derived from a C-terminal Peptide Helix

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Creator:

Gavenonis, Jason, Kritzer, Joshua A., and Jonas, Nicholas E.

Description:

Published as: Gavenonis, Jason, Nicholas E. Jonas, and Joshua A. Kritzer. Potential C-terminal-domain Inhibitors of Heat Shock Protein 90 Derived from a C-terminal Peptide Helix. Bioorganic and Medicinal Chemistry 22, no.15...

Type:

Article